Genomes of giant tortoises tell us about cancer and longevity!

Our comparative genomics study informs about evolutionary mechanisms linked to cancer resistance and longevity in giant tortoises. A fascinating study led by colleagues at Yale University and Universidad de Oviedo that has generated huge media attention worldwide, including an editorial in Nature and an article in the New York Times.

The paper is open access.

Quesada V, Freitas-Rodríguez S, Miller J, Pérez-Silva J, Jiang Z, Tapia W, Santiago-Fernández O, Campos-Iglesias D, Kuderna L, Quinzin M, Álvarez M, Carrero D, Beheregaray LB, Gibbs J, Chiari Y, Glaberman S, Ciofi C, Araujo-Voces M, Mayoral P, Arango J, Tamargo-Gómez I, Roiz-Valle D, Pascual-Torner M, Evans B, Edwards D, Garrick R, Russello M, Poulakakis N, Gaughran S, Rueda D, Bretones G, Marques-Bonet T, White K, Caccone A, Lopez-Otin C
(2018) Giant tortoise genomes provide insights into longevity and age-related disease. 
Nature Ecology & Evolution